|
rs9939609
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Diabetes genomics research has illuminated single nucleotide polymorphism (SNP) in several genes including, fat mass and obesity associated (FTO) (rs9939609 and rs9926289), potassium voltage-gated channel subfamily J member 11 (rs5219), SLC30A 8 (rs13266634) and peroxisome proliferator-activated receptor gamma 2 (rs1805192).
|
31823921 |
2019 |
|
rs13266634
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Diabetes genomics research has illuminated single nucleotide polymorphism (SNP) in several genes including, fat mass and obesity associated (FTO) (rs9939609 and rs9926289), potassium voltage-gated channel subfamily J member 11 (rs5219), SLC30A 8 (rs13266634) and peroxisome proliferator-activated receptor gamma 2 (rs1805192).
|
31823921 |
2019 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Diabetes genomics research has illuminated single nucleotide polymorphism (SNP) in several genes including, fat mass and obesity associated (FTO) (rs9939609 and rs9926289), potassium voltage-gated channel subfamily J member 11 (rs5219), SLC30A 8 (rs13266634) and peroxisome proliferator-activated receptor gamma 2 (rs1805192).
|
31823921 |
2019 |
|
rs5219
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Diabetes genomics research has illuminated single nucleotide polymorphism (SNP) in several genes including, fat mass and obesity associated (FTO) (rs9939609 and rs9926289), potassium voltage-gated channel subfamily J member 11 (rs5219), SLC30A 8 (rs13266634) and peroxisome proliferator-activated receptor gamma 2 (rs1805192).
|
31823921 |
2019 |
|
rs9926289
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Diabetes genomics research has illuminated single nucleotide polymorphism (SNP) in several genes including, fat mass and obesity associated (FTO) (rs9939609 and rs9926289), potassium voltage-gated channel subfamily J member 11 (rs5219), SLC30A 8 (rs13266634) and peroxisome proliferator-activated receptor gamma 2 (rs1805192).
|
31823921 |
2019 |
|
rs1333049
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Genotype CC of rs1333049 was significantly associated with both elevated CRP levels and decreased HDL concentrations after univariate (p = 0.028, p = 0.012) and multivariate analysis (p = 0.041, p = 0.023) stratified for age, gender, body mass index, smoking, diabetes, and severe periodontitis.
|
31770616 |
2020 |
|
rs7903146
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There is a trend toward an association between faster GE and the diabetes-associated allele at rs7903146 in TCF7L2.
|
31691451 |
2020 |
|
rs550057
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetically instrumented blood lead was not associated with CAD (odds ratio (OR) 1.01 per effect size of log transformed blood lead, 95% confidence interval (CI) 0.97, 1.05), blood pressure (systolic -0.18 mmHg, 95% CI -0.44 to 0.08 and diastolic -0.03 mmHg, 95% CI -0.09 to 0.15) or diabetes (OR 0.98, 95% CI 0.92 to 1.03) using MR-PRESSO estimates corrected for an outlier SNP (rs550057) from the highly pleiotropic gene ABO.
|
31690775 |
2019 |
|
rs201264306
|
|
|
0.020 |
GeneticVariation |
BEFREE |
One novel mutation (p.I99_C100insSI) and three previously reported variants (p.G32S, p.R89C and p.C96R) in INS were identified in four infants with early-onset diabetes.
|
31605659 |
2019 |
|
rs372098146
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we expressed, in dPdxk<sup>1</sup> mutant flies, four PDXK human variants: three (D87H, V128I and H246Q) listed in databases, and one (A243G) found in a genetic screening in patients with diabetes.
|
31578392 |
2019 |
|
rs377592729
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we expressed, in dPdxk<sup>1</sup> mutant flies, four PDXK human variants: three (D87H, V128I and H246Q) listed in databases, and one (A243G) found in a genetic screening in patients with diabetes.
|
31578392 |
2019 |
|
rs2910164
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis indicated that miRNA27a rs895819 might play a protective role in diabetes, and miRNA146a rs2910164 likely had no association with diabetes.
|
31577754 |
2019 |
|
rs895819
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis indicated that miRNA27a rs895819 might play a protective role in diabetes, and miRNA146a rs2910164 likely had no association with diabetes.
|
31577754 |
2019 |
|
rs1060366
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, allele A of G94A SNP (rs1060366) could be a risk allele for diabetes susceptibility among Egyptian patients.
|
31523248 |
2019 |
|
rs149131600
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
|
31511532 |
2019 |
|
rs17137004
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
|
31511532 |
2019 |
|
rs4258701
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
|
31511532 |
2019 |
|
rs59825600
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
|
31511532 |
2019 |
|
rs6688849
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
|
31511532 |
2019 |
|
rs6706313
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
|
31511532 |
2019 |
|
rs74375025
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
|
31511532 |
2019 |
|
rs780093
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
|
31511532 |
2019 |
|
rs1333049
|
|
|
0.740 |
GeneticVariation |
BEFREE |
For CHD patients, rs1333049 decreased the risk of diabetes under heterozygote (p = .014) and dominant (p = .024) models.
|
31496134 |
2019 |
|
rs28938469
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We explored the gene responsible for diabetes in two brothers, who were suspected to have diabetes </span>at 15 and 18 years-of-age, respectively, with whole exome sequencing, and identified a compound heterozygous ABCC8 gene mutation (p.Arg168Cys and p.Arg1421Cys).
|
31479591 |
2020 |
|
rs756823374
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We explored the gene responsible for diabetes in two brothers, who were suspected to have diabetes at 15 and 18 years-of-age, respectively, with whole exome sequencing, and identified a compound heterozygous ABCC8 gene mutation (p.Arg168Cys and p.Arg1421Cys).
|
31479591 |
2020 |